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Compounds

COMPOUND NPA004506

STRUCTURE
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PROPERTIES
NPAID NPA004506
CLUSTER ID 1211
NODE ID 1030
NAME Ustiloxin D
FORMULA C23H34N4O8
MOLECULAR WEIGHT (Da) 494.5450
ACCURATE MASS (Da) 494.2377
ORIGIN ORGANISM TYPE Fungus
ORIGIN GENUS Ustilaginoidea
ORIGIN SPECIES virens
InChIKey GDXLZSYACWZHOC-ZNRYNLAGSA-N
InChI InChI=1S/C23H34N4O8/c1-6-23(4)19(22(34)25-10-15(29)30)27-20(32)16(11(2)3)26-21(33)17(24-5)18(31)12-7-8-13(28)14(9-12)35-23/h7-9,11,16-19,24,28,31H,6,10H2,1-5H3,(H,25,34)(H,26,33)(H,27,32)(H,29,30)/t16-,17-,18+,19+,23+/m0/s1
SMILES CC[C@@]1([C@H](NC(=O)[C@@H](NC(=O)[C@H]([C@@H](C2=CC(=C(C=C2)O)O1)O)NC)C(C)C)C(=O)NCC(=O)O)C
ORIGINAL ISOLATION REFERENCE
CITATION Koiso; Li; Iwasaki; Hanaoka; Kobayashi; Sonoda; Fujita; Yaegashi; Sato Ustiloxins, antimitotic cyclic peptides from false smut balls on rice panicles caused by Ustilaginoidea virens Journal of Antibiotics 1994 47 (7) 765-773.
DOI 10.7164/antibiotics.47.765 PMID 8071121
ORIGINAL ISOLATION TAXONOMY
RANK NAME DB LINK NCBI
Domain Eukarya - 2759
Kingdom Fungi MycoBank 4751
Phylum Ascomycota MycoBank 4890
Class Sordariomycetes MycoBank 147550
Order Hypocreales MycoBank 5125
Genus Ustilaginoidea MycoBank 124426
SYNTHESES
CITATION 1 Cao B; Park H; Joullié MM Total synthesis of ustiloxin D. Journal of the American Chemical Society 2002 124 (4) 520-521. DOI: 10.1021/ja017277z PMID: 11804473
CITATION 2 Tanaka H; Sawayama AM; Wandless TJ Enantioselective total synthesis of ustiloxin D. Journal of the American Chemical Society 2003 125 (23) 6864-6865. DOI: 10.1021/ja035429f PMID: 12783528
CITATION 3 Brown AL; Churches QI; Hutton CA Total Synthesis of Ustiloxin D Utilizing an Ammonia-Ugi Reaction. Journal of Organic Chemistry 2015 80 (20) 9831-9837. DOI: 10.1021/acs.joc.5b01519 PMID: 26394038
CITATION 4 Li P; Evans CD; Joullié MM A convergent total synthesis of ustiloxin D via an unprecedented copper-catalyzed ethynyl aziridine ring-opening by phenol derivatives. Organic Letters 2005 7 (23) 5325-5327. DOI: 10.1021/ol052287g PMID: 16268569
CITATION 5 Sawayama AM; Tanaka H; Wandless TJ Total synthesis of ustiloxin D and considerations on the origin of selectivity of the asymmetric allylic alkylation. Journal of Organic Chemistry 2004 69 (25) 8810-8820. DOI: 10.1021/jo048854f PMID: 15575762
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