Compounds
| ID | Spectrum Quality | Annotated Name |
|---|
COMPOUND NPA033054
PROPERTIES
| NPAID | NPA033054 |
|---|---|
| CLUSTER ID | 9531 |
| NODE ID | 6381 |
| NAME | Corbomycin |
| FORMULA | C79H66N10O22 |
| MOLECULAR WEIGHT (Da) | 1507.4450 |
| ACCURATE MASS (Da) | 1506.4353 |
| ORIGIN ORGANISM TYPE | Bacterium |
| ORIGIN GENUS | Streptomyces |
| ORIGIN SPECIES | sp. WAC01529 |
| InChIKey | YPKFJNUZFFXJND-OUBAQASASA-N |
| InChI | InChI=1S/C79H66N10O22/c1-33(90)81-64(36-5-9-43(91)10-6-36)76(105)86-66-40-21-46(94)29-49(22-40)111-61-26-38(8-15-59(61)97)65-77(106)87-67-41-23-51(37-7-13-50-42(32-80-54(50)24-37)25-57(73(102)85-65)84-74(66)103)70(99)62(27-41)110-48-11-2-34(3-12-48)17-55-72(101)89-69(78(107)88-68(79(108)109)39-19-44(92)28-45(93)20-39)53-30-47(95)31-60(98)63(53)52-16-35(4-14-58(52)96)18-56(71(100)82-55)83-75(67)104/h2-16,19-24,26-32,55-57,64-69,80,91-99H,17-18,25H2,1H3,(H,81,90)(H,82,100)(H,83,104)(H,84,103)(H,85,102)(H,86,105)(H,87,106)(H,88,107)(H,89,101)(H,108,109)/t55-,56+,57+,64-,65+,66-,67+,68-,69-/m0/s1 |
| SMILES | CC(=O)N[C@H](C(=O)N[C@@H]1C(=O)N[C@@H]2CC3=CNC4=C3C=CC(=C4)C3=CC4=CC(=C3O)OC3=CC=C(C=C3)C[C@@H]3NC(=O)[C@@H](CC5=CC=C(O)C(=C5)C5=C(C=C(O)C=C5O)[C@@H](C(=O)N[C@H](C(=O)O)C5=CC(O)=CC(O)=C5)NC3=O)NC(=O)[C@@H]4NC(=O)[C@H](NC2=O)C2=CC(=C(O)C=C2)OC2=CC1=CC(O)=C2)C1=CC=C(O)C=C1 |
ORIGINAL ISOLATION REFERENCE
| CITATION | Culp, Elizabeth J; Waglechner, Nicholas; Wang, Wenliang; Fiebig-Comyn, Aline A; Hsu, Yen-Pang; Koteva, Kalinka; Sychantha, David; Coombes, Brian K; Van Nieuwenhze, Michael S; Brun, Yves V; Wright, Gerard D Evolution-guided discovery of antibiotics that inhibit peptidoglycan remodelling. Nature 2020 578 (7796) 582-587. | ||
|---|---|---|---|
| DOI | 10.1038/s41586-020-1990-9 | PMID | 32051588 |
