Compounds
| ID | Spectrum Quality | Annotated Name |
|---|
COMPOUND NPA031553
PROPERTIES
| NPAID | NPA031553 |
|---|---|
| CLUSTER ID | 9183 |
| NODE ID | 6166 |
| NAME | Rhizolutin |
| FORMULA | C21H28O5 |
| MOLECULAR WEIGHT (Da) | 360.4500 |
| ACCURATE MASS (Da) | 360.1937 |
| ORIGIN ORGANISM TYPE | Bacterium |
| ORIGIN GENUS | Streptomyces |
| ORIGIN SPECIES | sp. |
| InChIKey | GSVYLEFSSDOSSC-RRQVMCLOSA-N |
| InChI | InChI=1S/C21H28O5/c1-4-16-11-17-13(3)8-19-14(9-15(22)10-20(23)26-19)6-5-12(2)7-18(17)21(24)25-16/h5-8,14-19,22H,4,9-11H2,1-3H3/t14-,15-,16+,17-,18-,19+/m1/s1 |
| SMILES | CC[C@H]1C[C@@H]2C(C)=C[C@@H]3OC(=O)C[C@H](O)C[C@H]3C=CC(C)=C[C@H]2C(=O)O1 |
ORIGINAL ISOLATION REFERENCE
| CITATION | Kwon, Yun; Shin, Jisu; Nam, Kwangho; An, Joon Soo; Yang, Seung-Hoon; Hong, Seong-Heon; Bae, Munhyung; Moon, Kyuho; Cho, Yakdol; Woo, Jiwan; Park, Keunwan; Kim, Kyeonghwan; Shin, Jongheon; Kim, Byung-Yong; Kim, YoungSoo; Oh, Dong-Chan Rhizolutin, a Novel 7/10/6-Tricyclic Dilactone, Dissociates Misfolded Protein Aggregates and Reduces Apoptosis/Inflammation Associated with Alzheimer's Disease. Angewandte Chemie International Edition 2020 59 (51) 22994-22998. | ||
|---|---|---|---|
| DOI | 10.1002/anie.202009294 | PMID | 32844539 |
REVISIONS
| VERSION | SMILES | CITATION | ||
|---|---|---|---|---|
| Original Isolation | CC[C@H]1C[C@@H]2C(C)=C[C@@H]3OC(=O)C[C@@H](O)C[C@H]3C=CC(C)=C[C@H]2C(=O)O1 | Kwon, Yun; Shin, Jisu; Nam, Kwangho; An, Joon Soo; Yang, Seung-Hoon; Hong, Seong-Heon; Bae, Munhyung; Moon, Kyuho; Cho, Yakdol; Woo, Jiwan; Park, Keunwan; Kim, Kyeonghwan; Shin, Jongheon; Kim, Byung-Yong; Kim, YoungSoo; Oh, Dong-Chan Rhizolutin, a Novel 7/10/6-Tricyclic Dilactone, Dissociates Misfolded Protein Aggregates and Reduces Apoptosis/Inflammation Associated with Alzheimer's Disease. Angewandte Chemie International Edition 2020 59 (51) 22994-22998. DOI: 10.1002/anie.202009294 PMID: 32844539 | ||
| 2 | CC[C@H]1C[C@@H]2C(C)=C[C@@H]3OC(=O)C[C@H](O)C[C@H]3C=CC(C)=C[C@H]2C(=O)O1 | Schmid, Julian C; Frey, Kerstin; Scheiner, Matthias; Garzón, Jaime Felipe Guerrero; Stafforst, Luise; Fricke, Jan-Niklas; Schuppe, Michaela; Schiewe, Hajo; Zeeck, Axel; Weber, Tilmann; Usón, Isabel; Kemkemer, Ralf; Decker, Michael; Grond, Stephanie The Structure of Cyclodecatriene Collinolactone, its Biosynthesis, and Semisynthetic Analogues: Effects of Monoastral Phenotype and Protection from Intracellular Oxidative Stress. Angewandte Chemie International Edition 2021 60 (43) 23212-23216. DOI: 10.1002/anie.202106802 PMID: 34415670 | ||
