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Compounds

COMPOUND NPA020303

STRUCTURE
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PROPERTIES
NPAID NPA020303
CLUSTER ID 193
NODE ID 181
NAME Brevianamide B
FORMULA C21H23N3O3
MOLECULAR WEIGHT (Da) 365.4330
ACCURATE MASS (Da) 365.1739
ORIGIN ORGANISM TYPE Fungus
ORIGIN GENUS Penicillium
ORIGIN SPECIES brevi-compactum Dierckx
InChIKey MWOFPQAPILIIPR-LYARXQMPSA-N
InChI InChI=1S/C21H23N3O3/c1-18(2)14-10-19-8-5-9-24(19)17(27)20(14,23-16(19)26)11-21(18)15(25)12-6-3-4-7-13(12)22-21/h3-4,6-7,14,22H,5,8-11H2,1-2H3,(H,23,26)/t14-,19+,20+,21+/m1/s1
SMILES CC1([C@H]2C[C@]34CCCN3C(=O)[C@@]2(C[C@]15C(=O)C6=CC=CC=C6N5)NC4=O)C
ORIGINAL ISOLATION REFERENCE
CITATION Birch, AJ; Russel, RA Studies in relation to biosynthesis—XLIV : Structural elucidations of brevianamides-B, -C, -D and -F Tetrahedron 1972 28 (11) 2999-3008.
DOI 10.1016/0040-4020(72)80014-0 PMID -
ORIGINAL ISOLATION TAXONOMY
RANK NAME DB LINK NCBI
Domain Eukarya - 2759
Kingdom Fungi MycoBank 4751
Phylum Ascomycota MycoBank 4890
Class Eurotiomycetes MycoBank 147545
Order Eurotiales MycoBank 5042
Family Aspergillaceae MycoBank 1131492
Genus Penicillium MycoBank 5073
SYNTHESES
CITATION 1 Robins JG; Kim KJ; Chinn AJ; Woo JS; Scheerer JR Intermolecular Diels-Alder Cycloaddition for the Construction of Bicyclo[2.2.2]diazaoctane Structures: Formal Synthesis of Brevianamide B and Premalbrancheamide. Journal of Organic Chemistry 2016 81 (6) 2293-301. DOI: 10.1021/acs.joc.5b02744 PMID: 26916112
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