Compounds
| ID | Spectrum Quality | Annotated Name |
|---|---|---|
| CCMSLIB00000424847 | Bronze | Dendroamide&A |
| CCMSLIB00000424848 | Bronze | Dendroamide&A |
COMPOUND NPA018872
PROPERTIES
| NPAID | NPA018872 |
|---|---|
| CLUSTER ID | 275 |
| NODE ID | 249 |
| NAME | Dendroamide A |
| FORMULA | C21H24N6O4S2 |
| MOLECULAR WEIGHT (Da) | 488.5950 |
| ACCURATE MASS (Da) | 488.1300 |
| ORIGIN ORGANISM TYPE | Bacterium |
| ORIGIN GENUS | Stigonema |
| ORIGIN SPECIES | dendroideum |
| InChIKey | MDIRDFOZMJDCMK-GPCCPHFNSA-N |
| InChI | InChI=1S/C21H24N6O4S2/c1-8(2)14-21-25-13(7-33-21)17(29)23-10(4)20-24-12(6-32-20)16(28)22-9(3)19-27-15(11(5)31-19)18(30)26-14/h6-10,14H,1-5H3,(H,22,28)(H,23,29)(H,26,30)/t9-,10-,14-/m1/s1 |
| SMILES | C[C@@H]1C2=NC(=C(O2)C)C(=O)N[C@@H](C3=NC(=CS3)C(=O)N[C@@H](C4=NC(=CS4)C(=O)N1)C)C(C)C |
ORIGINAL ISOLATION REFERENCE
| CITATION | Ogino, Junichi; Moore, Richard E.; Patterson, Gregory M. L.; Smith, Charles D. Dendroamides, new cyclic hexapeptides from a blue-green alga. Multidrug- resistance reversing activity of dendroamide A Journal of Natural Products 1996 59 (6) 581-586. | ||
|---|---|---|---|
| DOI | 10.1021/np960178s | PMID | 8786364 |
SYNTHESES
| CITATION 1 | You SL; Kelly JW Total synthesis of dendroamide a: oxazole and thiazole construction using an oxodiphosphonium salt. Journal of Organic Chemistry 2003 68 (24) 9506-9509. DOI: 10.1021/jo0302657 PMID: 14629183 | ||
|---|---|---|---|
| CITATION 2 | Xia Z; Smith CD Total synthesis of dendroamide A, a novel cyclic peptide that reverses multiple drug resistance. Journal of Organic Chemistry 2001 66 (10) 3459-3466. DOI: 10.1021/jo005783l PMID: 11348130 | ||
