Compounds
| ID | Spectrum Quality | Annotated Name |
|---|
COMPOUND NPA017441
PROPERTIES
| NPAID | NPA017441 |
|---|---|
| CLUSTER ID | 5856 |
| NODE ID | 4118 |
| NAME | Flutimide |
| FORMULA | C12H18N2O3 |
| MOLECULAR WEIGHT (Da) | 238.2870 |
| ACCURATE MASS (Da) | 238.1317 |
| ORIGIN ORGANISM TYPE | Fungus |
| ORIGIN GENUS | Delitschia |
| ORIGIN SPECIES | confertaspora |
| InChIKey | SIXHCCPAJIVTOY-UITAMQMPSA-N |
| InChI | InChI=1S/C12H18N2O3/c1-7(2)5-9-11(15)14(17)12(16)10(13-9)6-8(3)4/h5,7-8,17H,6H2,1-4H3/b9-5- |
| SMILES | CC(C)CC1=N/C(=C\C(C)C)/C(=O)N(C1=O)O |
ORIGINAL ISOLATION REFERENCE
| CITATION | Hensens, Otto D.; Goetz, Michael A.; Liesch, Jerrold M.; Zink, Deborah L.; Raghoobar, Susan L.; et al. Isolation and Structure of Flutimide, a Novel Endonuclease Inhibitor of Influenza Virus Tetrahedron Letters 1995 36 (12) 2005-2008. | ||
|---|---|---|---|
| DOI | 10.1016/0040-4039(95)00213-v | PMID | - |
SYNTHESES
| CITATION 1 | Singh SB; Tomassini JE Synthesis of natural flutimide and analogous fully substituted pyrazine-2,6-diones, endonuclease inhibitors of influenza virus. Journal of Organic Chemistry 2001 66 (16) 5504-5516. DOI: 10.1021/jo015665d PMID: 11485475 | ||
|---|---|---|---|
