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Compounds

COMPOUND NPA016262

STRUCTURE
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PROPERTIES
NPAID NPA016262
CLUSTER ID 687
NODE ID 606
NAME Benzastatin E
FORMULA C19H28N2O3
MOLECULAR WEIGHT (Da) 332.4440
ACCURATE MASS (Da) 332.2100
ORIGIN ORGANISM TYPE Bacterium
ORIGIN GENUS Streptomyces
ORIGIN SPECIES nitrosporeus
InChIKey OTZRBYNNRWOBRT-HKUYNNGSSA-N
InChI InChI=1S/C19H28N2O3/c1-12(2)13(3)7-8-19(23,11-24-4)17-10-15-9-14(18(20)22)5-6-16(15)21-17/h5-6,9,17,21,23H,7-8,10-11H2,1-4H3,(H2,20,22)/t17-,19-/m0/s1
SMILES COC[C@@](O)(CCC(C)=C(C)C)[C@@H]1CC2=C(C=CC(C(N)=O)=C2)N1
ORIGINAL ISOLATION REFERENCE
CITATION Kim, Won-Gon; Kim, Jong-Pyung; Koshino, Hiroyuki; Shin-Ya, Kazuo; Seto, Haruo; Yoo, Ick-Dong Benzastatins E, F, and G: new indoline alkaloids with neuronal cell protecting activity from Streptomyces nitrosporeus Tetrahedron 1997 53 (12) 4309-4316.
DOI 10.1016/s0040-4020(97)00157-9 PMID -
ORIGINAL ISOLATION TAXONOMY
RANK NAME DB LINK NCBI
Domain Bacteria LPSN 2
Phylum Actinobacteria LPSN 201174
Class Actinobacteria LPSN -
Order Streptomycetales LPSN 85011
Family Streptomycetaceae LPSN 2062
Genus Streptomyces LPSN 1883
SYNTHESES
CITATION 1 Toda N; Ori M; Takami K; Tago K; Kogen H Total synthesis of (+)-benzastatin E via diastereoselective Grignard addition to 2-acylindoline. Organic Letters 2003 5 (3) 269-71. DOI: 10.1021/ol027215t PMID: 12556169
REVISIONS
VERSION SMILES CITATION
Original Isolation CC(=C(C)CCC(COC)([C@H]1CC2=C(N1)C=CC(=C2)C(=O)N)O)C Kim, Won-Gon; Kim, Jong-Pyung; Koshino, Hiroyuki; Shin-Ya, Kazuo; Seto, Haruo; Yoo, Ick-Dong Benzastatins E, F, and G: new indoline alkaloids with neuronal cell protecting activity from Streptomyces nitrosporeus Tetrahedron 1997 53 (12) 4309-4316. DOI: 10.1016/s0040-4020(97)00157-9
2 COC[C@@](O)(CCC(C)=C(C)C)[C@@H]1CC2=C(C=CC(C(N)=O)=C2)N1 Toda N; Ori M; Takami K; Tago K; Kogen H Total synthesis of (+)-benzastatin E via diastereoselective Grignard addition to 2-acylindoline. Organic Letters 2003 5 (3) 269-71. DOI: 10.1021/ol027215t PMID: 12556169
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