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Compounds

COMPOUND NPA006331

STRUCTURE
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PROPERTIES
NPAID NPA006331
CLUSTER ID 2957
NODE ID 398
NAME Decarestrictine D
FORMULA C10H16O5
MOLECULAR WEIGHT (Da) 216.2330
ACCURATE MASS (Da) 216.0998
ORIGIN ORGANISM TYPE Fungus
ORIGIN GENUS Penicillium
ORIGIN SPECIES sp.
InChIKey HWMMWMJBUOCCFZ-HXFLIBJXSA-N
InChI InChI=1S/C10H16O5/c1-6-4-7(11)2-3-8(12)9(13)5-10(14)15-6/h2-3,6-9,11-13H,4-5H2,1H3/t6-,7-,8+,9+/m1/s1
SMILES C[C@@H]1C[C@H](O)C=C[C@H](O)[C@@H](O)CC(=O)O1
ORIGINAL ISOLATION REFERENCE
CITATION Göhrt, A; Zeeck, A; Hütter, K; Kirsch, R; Kluge, H; Thiericke, R Secondary metabolites by chemical screening. 9. Decarestrictines, a new family of inhibitors of cholesterol biosynthesis from Penicillium. II. Structure elucidation of the decarestrictines A to D. Journal of Antibiotics 1992 45 (1) 66-73.
DOI 10.7164/antibiotics.45.66 PMID 1548191
ORIGINAL ISOLATION TAXONOMY
RANK NAME DB LINK NCBI
Domain Eukarya - 2759
Kingdom Fungi MycoBank 4751
Phylum Ascomycota MycoBank 4890
Class Eurotiomycetes MycoBank 147545
Order Eurotiales MycoBank 5042
Family Aspergillaceae MycoBank 1131492
Genus Penicillium MycoBank 5073
SYNTHESES
CITATION 1 Binanzer M; Fang GY; Aggarwal VK Asymmetric synthesis of allylsilanes by the borylation of lithiated carbamates: formal total synthesis of (-)-decarestrictine D. Angewandte Chemie International Edition 2010 49 (25) 4264-8. DOI: 10.1002/anie.201001223 PMID: 20446329
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