Compounds
| ID | Spectrum Quality | Annotated Name |
|---|
COMPOUND NPA002215
PROPERTIES
| NPAID | NPA002215 |
|---|---|
| CLUSTER ID | 1337 |
| NODE ID | 1128 |
| NAME | Antascomicin B |
| FORMULA | C37H57NO10 |
| MOLECULAR WEIGHT (Da) | 675.8600 |
| ACCURATE MASS (Da) | 675.3982 |
| ORIGIN ORGANISM TYPE | Bacterium |
| ORIGIN GENUS | Micromonospora |
| ORIGIN SPECIES | sp. A92-306401 |
| InChIKey | PSAJCYLXNSDJCJ-NXQCLTBJSA-N |
| InChI | InChI=1S/C37H57NO10/c1-22-11-7-5-6-8-13-28(39)25(4)31-19-15-24(3)37(46,48-31)34(43)35(44)38-20-10-9-12-27(38)36(45)47-30(18-14-22)23(2)21-26-16-17-29(40)33(42)32(26)41/h7-8,11,13,22-27,29-33,40-42,46H,5-6,9-10,12,14-21H2,1-4H3/b11-7+,13-8+/t22-,23-,24-,25+,26+,27+,29-,30+,31+,32+,33+,37-/m1/s1 |
| SMILES | C[C@H]\1CC[C@H](OC(=O)[C@@H]2CCCCN2C(=O)C(=O)[C@]3([C@@H](CC[C@H](O3)[C@H](C(=O)/C=C/CC/C=C1)C)C)O)[C@H](C)C[C@@H]4CC[C@H]([C@@H]([C@H]4O)O)O |
ORIGINAL ISOLATION REFERENCE
| CITATION | Fehr; Sanglier; Schuler; Gschwind; Ponelle; Schilling; Wioland Antascomicins A, B, C, D and E. Novel FKBP12 binding compounds from a Micromonospora strain Journal of Antibiotics 1996 49 (3) 230-233. | ||
|---|---|---|---|
| DOI | 10.7164/antibiotics.49.230 | PMID | 8626235 |
SYNTHESES
| CITATION 1 | Brittain DE; Griffiths-Jones CM; Linder MR; Smith MD; McCusker C; Barlow JS; Akiyama R; Yasuda K; Ley SV Total synthesis of antascomicin B. Angewandte Chemie International Edition 2005 44 (18) 2732-2737. DOI: 10.1002/anie.200500174 PMID: 15806607 | ||
|---|---|---|---|
