Compounds
| ID | Spectrum Quality | Annotated Name |
|---|
COMPOUND NPA001619
PROPERTIES
| NPAID | NPA001619 |
|---|---|
| CLUSTER ID | 1042 |
| NODE ID | 897 |
| NAME | Argifin |
| FORMULA | C29H41N9O10 |
| MOLECULAR WEIGHT (Da) | 675.7000 |
| ACCURATE MASS (Da) | 675.2976 |
| ORIGIN ORGANISM TYPE | Fungus |
| ORIGIN GENUS | Gliocladium |
| ORIGIN SPECIES | sp. FTD-0668 |
| InChIKey | UHBHXSDKGLPPGO-ABHMUUKNSA-N |
| InChI | InChI=1S/C29H41N9O10/c1-15-23(41)35-17(10-7-11-32-28(30)37-29(48)31-2)25(43)38(3)20(12-16-8-5-4-6-9-16)24(42)36-19(27(46)47)14-22(40)34-18(26(44)45)13-21(39)33-15/h4-6,8-9,15,17-20H,7,10-14H2,1-3H3,(H,33,39)(H,34,40)(H,35,41)(H,36,42)(H,44,45)(H,46,47)(H4,30,31,32,37,48)/t15-,17+,18-,19+,20+/m0/s1 |
| SMILES | C[C@H]1C(=O)N[C@@H](C(=O)N([C@@H](C(=O)N[C@H](CC(=O)N[C@@H](CC(=O)N1)C(=O)O)C(=O)O)CC2=CC=CC=C2)C)CCCN=C(N)NC(=O)NC |
ORIGINAL ISOLATION REFERENCE
| CITATION | Arai, Noriko; Shiomi, Kazuro; Iwai, Yuzuru; Oemura, Satoshi Argifin, a new chitinase inhibitor, produced by Gliocladium sp. FTD-0668 II. Isolation, physico-chemical properties, and structure elucidation Journal of Antibiotics 2000 53 (6) 609-614. | ||
|---|---|---|---|
| DOI | 10.7164/antibiotics.53.609 | PMID | 10966077 |
SYNTHESES
| CITATION 1 | Sunazuka T; Sugawara A; Iguchi K; Hirose T; Nagai K; Noguchi Y; Saito Y; Yamamoto T; Ui H; Gouda H; Shiomi K; Watanabe T; Omura S Argifin; efficient solid phase total synthesis and evaluation of analogues of acyclic peptide. Bioorganic and Medicinal Chemistry 2009 17 (7) 2751-2758. DOI: 10.1016/j.bmc.2009.02.047 PMID: 19297173 | ||
|---|---|---|---|
| CITATION 2 | Hirose T; Sunazuka T; Omura S Recent development of two chitinase inhibitors, Argifin and Argadin, produced by soil microorganisms. Proceedings of the Japan Academy, Ser. B, Physical and Biological Sciences 2010 86 (2) 85-102. DOI: 10.2183/pjab.86.85 PMID: 20154467 | ||
