Compounds
| ID | Spectrum Quality | Annotated Name |
|---|
COMPOUND NPA001518
PROPERTIES
| NPAID | NPA001518 |
|---|---|
| CLUSTER ID | 986 |
| NODE ID | 850 |
| NAME | EI-1941-1 |
| FORMULA | C12H16O5 |
| MOLECULAR WEIGHT (Da) | 240.2550 |
| ACCURATE MASS (Da) | 240.0998 |
| ORIGIN ORGANISM TYPE | Fungus |
| ORIGIN GENUS | Farrowia |
| ORIGIN SPECIES | sp. E-1941 |
| InChIKey | DJMYUSHSKVTQAD-UHFFFAOYSA-N |
| InChI | InChI=1S/C12H16O5/c1-2-3-5-4-6-7(12(15)16-5)9(14)11-10(17-11)8(6)13/h5,9-12,14-15H,2-4H2,1H3 |
| SMILES | CCCC1CC2=C(C(C3C(C2=O)O3)O)C(O1)O |
ORIGINAL ISOLATION REFERENCE
| CITATION | Koizumi, Fumito; Matsuda, Yuzuru; Nakanishi, Satoshi EI-1941-1 and -2, novel interleukin-1β converting enzyme inhibitors produced by Farrowia sp. E-1941. I. Biochemical characterization of EI-1941-1 and -2 Journal of Antibiotics 2003 56 (5) 464-469. | ||
|---|---|---|---|
| DOI | 10.7164/antibiotics.56.464 | PMID | 12870812 |
SYNTHESES
| CITATION 1 | Shoji M; Uno T; Kakeya H; Onose R; Shiina I; Osada H; Hayashi Y Enantio- and diastereoselective total synthesis of EI-1941-1, -2, and -3, inhibitors of interleukin-1beta converting enzyme, and biological properties of their derivatives. Journal of Organic Chemistry 2005 70 (24) 9905-9915. DOI: 10.1021/jo0516436 PMID: 16292821 | ||
|---|---|---|---|
