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Péduzzi, Jean; Goulard, Christophe; Chiuchiolo, María J; Barthélémy, Michel; Prigent, Yann; Salomón, Raúl A; Farías, Ricardo N; Moreno, Felipe; Rebuffat, Sylvie","title":"The cyclic structure of microcin J25, a 21-residue peptide antibiotic from Escherichia coli","journal":"European Journal of Biochemistry","year":1999,"volume":"259","issue":"3","pages":"747-756"},"origin_organism":{"id":294,"type":"Bacterium","genus":"Escherichia","species":"coli","taxon":{"id":91,"name":"Escherichia","rank":"genus","taxon_db":"lpsn","external_id":"515602","ncbi_id":561,"ancestors":[{"id":1,"name":"Bacteria","rank":"domain","taxon_db":"lpsn","external_id":"0","ncbi_id":2},{"id":2,"name":"Proteobacteria","rank":"phylum","taxon_db":"lpsn","external_id":"0","ncbi_id":1224},{"id":79,"name":"Gammaproteobacteria","rank":"class","taxon_db":"lpsn","external_id":"0","ncbi_id":1236},{"id":87,"name":"Enterobacterales","rank":"order","taxon_db":"lpsn","external_id":"0","ncbi_id":91347},{"id":88,"name":"Enterobacteriaceae","rank":"family","taxon_db":"lpsn","external_id":"0","ncbi_id":543}]}},"syntheses":[],"reassignments":[{"reference_doi":"10.1021/ja0367703","structure_smiles":"CCC(C)C(NC(=O)CNC(=O)C(NC(=O)C(CC1=CC=CC=C1)NC(=O)C(CC1=CC=C(O)C=C1)NC(=O)C1CCC(=O)NCC(=O)NCC(=O)NC(C)C(=O)NCC(=O)NC(CC2=CN=CN2)C(=O)NC(C(C)C)C(=O)N2CCCC2C(=O)N1)C(C)C)C(=O)NCC(=O)NC(C(=O)N1CCCC1C(=O)NC(C(=O)NC(CO)C(=O)NC(CC1=CC=CC=C1)C(=O)NC(CC1=CC=C(O)C=C1)C(=O)NCC(=O)O)C(C)CC)C(C)O"}],"mol_structures":[{"current_structure":false,"reference_doi":"10.1046/j.1432-1327.1999.00085.x","structure_smiles":"CCC(C)C1C(=O)NCC(=O)NC(C(=O)N2CCCC2C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NCC(=O)NCC(=O)NCC(=O)NC(C(=O)NCC(=O)NC(C(=O)NC(C(=O)N3CCCC3C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NCC(=O)N1)C(C)C)CC4=CC=CC=C4)CC5=CC=C(C=C5)O)CCC(=O)O)C(C)C)CC6=CN=CN6)C)CC7=CC=C(C=C7)O)CC8=CC=CC=C8)CO)C(C)CC)C(C)O","is_reassignment":false,"version":1},{"current_structure":true,"reference_doi":"10.1021/ja0367703","structure_smiles":"CCC(C)C(NC(=O)CNC(=O)C(NC(=O)C(CC1=CC=CC=C1)NC(=O)C(CC1=CC=C(O)C=C1)NC(=O)C1CCC(=O)NCC(=O)NCC(=O)NC(C)C(=O)NCC(=O)NC(CC2=CN=CN2)C(=O)NC(C(C)C)C(=O)N2CCCC2C(=O)N1)C(C)C)C(=O)NCC(=O)NC(C(=O)N1CCCC1C(=O)NC(C(=O)NC(CO)C(=O)NC(CC1=CC=CC=C1)C(=O)NC(CC1=CC=C(O)C=C1)C(=O)NCC(=O)O)C(C)CC)C(C)O","is_reassignment":true,"version":2}],"exclusions":[],"external_ids":[{"external_db_name":"mibig","external_db_code":"BGC0000581"},{"external_db_name":"npmrd","external_db_code":"NP0001582"}],"classyfire":{"class":{"url":"http://classyfire.wishartlab.com/tax_nodes/C0003298","name":"Polypeptides","chemont_id":"CHEMONTID:0003298","description":"Peptides containing ten or more amino acid residues."},"smiles":"CCC(C)C1NC(=O)CNC(=O)C(NC(=O)C(Cc2ccccc2)NC(=O)C(Cc2ccc(O)cc2)NC(=O)C(CCC(O)=O)NC(=O)C2CCCN2C(=O)C(NC(=O)C(Cc2cnc[nH]2)NC(=O)CNC(=O)C(C)NC(=O)CNC(=O)CNC(=O)CNC(=O)C(Cc2ccc(O)cc2)NC(=O)C(Cc2ccccc2)NC(=O)C(CO)NC(=O)C(NC(=O)C2CCCN2C(=O)C(NC(=O)CNC1=O)C(C)O)C(C)CC)C(C)C)C(C)C","kingdom":{"url":"http://classyfire.wishartlab.com/tax_nodes/C0000000","name":"Organic compounds","chemont_id":"CHEMONTID:0000000","description":"Compounds that contain at least one carbon atom, excluding isocyanide/cyanide and their non-hydrocarbyl derivatives, thiophosgene, carbon diselenide, carbon monosulfide, carbon disulfide, carbon subsulfide, carbon monoxide, carbon dioxide, Carbon suboxide, and dicarbon monoxide."},"inchikey":"InChIKey=TVZWTTNULXZYTK-UHFFFAOYSA-N","subclass":null,"ancestors":["1-hydroxy-2-unsubstituted benzenoids","Alcohols and polyols","Alpha amino acids and derivatives","Amino acids and derivatives","Amino acids, peptides, and analogues","Azacyclic compounds","Azoles","Benzene and substituted derivatives","Benzenoids","Carbonyl compounds","Carboxylic acid amides","Carboxylic acid derivatives","Carboxylic acids","Carboxylic acids and derivatives","Chemical entities","Cyclic peptides","Heteroaromatic compounds","Hydrocarbon derivatives","Imidazoles","Lactams","Monocarboxylic acids and derivatives","Organic Polymers","Organic acids and derivatives","Organic compounds","Organic nitrogen compounds","Organic oxides","Organic oxygen compounds","Organoheterocyclic compounds","Organonitrogen compounds","Organooxygen compounds","Organopnictogen compounds","Peptides","Phenols","Polypeptides","Primary alcohols","Pyrrolidines","Secondary alcohols","Secondary carboxylic acid amides","Tertiary carboxylic acid amides"],"superclass":{"url":"http://classyfire.wishartlab.com/tax_nodes/C0003297","name":"Organic Polymers","chemont_id":"CHEMONTID:0003297","description":"Organic compounds, generally large molecules or macromolecules, which are composed of many repeating units."},"description":"This compound belongs to the class of organic compounds known as polypeptides. 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